Low Testosterone Levels & COVID-19

Published on June 25th, 2020

A recent study has found that males with low testosterone levels are at greater risk of death from Covid-19. As we face the storm of this global pandemic and are constantly tossed new information on a daily basis, one thing has remained constant which is that certain age groups and those of ‘underlying issues’ are at far greater risk. Having low T levels can be an underlying issue and can be cause for concern. Low testosterone is closely aligned with the body’s immune system and when levels are too low, the immune system is at greater risk.

Read more on the study here:

“Watch the news and you will hear that many of the coronavirus patients that have died, had some type of underlying issues. Some of the medical issues were known, but some not. What happens when males suffer from low testosterone and contract COVID-19? According to German research, researchers found that a vast majority of men admitted had low testosterone levels fueling cytokine storms. We know that testosterone works hand in hand with the body’s immune system and when low, questionably low testosterone levels can lead to a cytokine storm within the body, which can sometimes prove fatal.
Male coronavirus patients with low testosterone levels are MORE likely to die from COVID-19, German hospital finds:
Men with low testosterone levels that contract COVID-19 are at far greater risk of dying from the virus, a study has found. A recent study found men are twice as likely to die from the coronavirus, but clinicians have been unable to determine why this is. But a study from a German hospital of 45 COVID-19 patients admitted to intensive care reveals the male sex hormone testosterone may play a key role.

The hormone is known to help regulate the body’s immune response but when a man has low levels of testosterone, the immune system is not kept in check and can go haywire following infection. This leads to a so-called cytokine storm which happens when the immune system goes out of control as it tries to kill the pathogen.A cytokine storm eventually begins damaging the body itself and, if left unchecked, can be fatal.

The researchers assessed the first 45 laboratory-confirmed COVID-19 patients admitted to the ICU at the University Medical Center Hamburg-Eppendorf. Thirty-five were men and ten were women, with seven patients requiring oxygen and 33 of them needing ventilation. Nine men and three women died. Hormone levels of each patient were assessed on their first day in ICU, before they had received any invasive procedures. Samples from the COVID-19 patients were tested for 12 hormones, including testosterone and dihydrotestosterone. Testosterone is key in how the body initiates and regulates various immune responses, including fighting viral infections. It plays a particular important role in men’s immunity as it is the main male sex hormone.

SARS-CoV-2 trigger’s the human body into producing vast amounts of cytokines, chemicals which flood to the site of infection and begin fighting the pathogen. They can also signal to the body to send more immune cells to mount a defence against a foreign invader. It is a key part of healing in humans but a common issue for patients diagnosed with COVID-19 is their immune system responds too aggressively.This can lead to this process getting out of control as it tries to defeat the invading pathogen. It leads to an enormous immune response called a cytokine storm. This is a hyperinflammatory condition itself and can lead to severe lung damage, acute respiratory distress syndrome (ARDS) and death.

Ali Daneshkhah, a postdoctoral research fellow at Northwestern University who was not involved in the study, explains: ‘This is what seems to kill a majority of COVID-19 patients, not the destruction of the lungs by the virus itself. It is the complications from the misdirected fire from the immune system. Professor Gabriel adds:

‘It seems that testosterone has a dampening impact on the virus induced cytokine storm, which finally leads to death in both cohorts. Men with normal testosterone levels do not present a cytokine storm and thus are more likely to survive.’

Writing in their study, which has not yet been peer-reviewed and scrutinised by independent academics, the medics say:

‘With SARS-CoV-2 continuing to infect humans worldwide, it was repeatedly reported that men with COVID-19 are at higher risk to develop severe and even lethal outcome compared to women, independent of age. Thus, it has become of utmost importance to understand why men are more likely to die from COVID-19 than women.The latest research builds on separate research, which Professor Gabriel was also involved in, which found men are also more likely to die after becoming infected with Avian influenza A (H7N9). Both these diseases are zoonotic — jumped into humans from animals — and are cytokine inducers, turning the body’s immune system against itself. The current hypothesis is that this “cytokine storm” inhibits steroid synthesis leading to low testosterone levels in men,’ says Professor Gabriel.

Of the male COVID-19 patients sent to ICU at the German hospital, more than two thirds (68.6 per cent) recorded low levels of testosterone. In contrast, the majority of female patients (60 per cent) had elevated testosterone levels. While low levels of testosterone can not control the immune response in men, the study found that in female COVID-19 patients, higher testosterone levels were linked to a more significant inflammatory response.

Professor Gülsah Gabriel from the Leibniz Institute for Experimental Virology in Hamburg, who was involved in the research, told MailOnline:

‘The majority of male COVID-19 patients had low testosterone levels. Of those male COVID-19 patients who died, the majority also had low testosterone levels. Thus, low testosterone levels in men seem to be a risk factor for severe and even fatal disease outcome in men upon infection with so-called “cytokine inducing” respiratory viruses.’

To get testosterone levels tested, schedule an appointment with the Low T Center nearest you today. To find that location > LOCATIONS

Devastating lung inflammation triggered by the so-called ‘cytokine storm‘ is thought to be what ultimately kills the sickest coronavirus patients. Cytokines are a group of cells involved in the immune system’s response to injury or infection. They race to the site of a problem and signal to the body to send more immune cells to mount a defense against a foreign invader. It’s a crucial part of how the body heals itself – but when it goes haywire it can lead to devastating damage. The influx of immune cells causes inflammation which, when persistent, and go awry and start killing cells in the very tissues the immune system is trying to protect. When overabundant signaling cytokine cells stay switched ‘on’ for too long inflammation can continue out of control. This inflammation overwhelms the lungs of coronavirus patients, sending them into respiratory failure and ultimately killing many of them if this inflammation can’t be stemmed.”

If you have experienced some of the common symptoms of low testosterone, call Chicagoland Men’s Health for a free consultation.

Back to News

Client Testimonials

I heard their radio ad on the way to work and they described everything i was feeling. I went in and within 2 weeks i was new man. 3 mos later i have lost almost 25 lbs and have way more energy and happiness. To say my love life is improved is an understatement lol. I feel 21 again--I strongly recommend this group. i know i am rambling but seriously i have never been happier. thank you CMH

~ Greg F. Ingleside, IL

Within 3 days of my first treatment I was off all other medication. My depression and insomnia were gone and I had more energy than I knew what to do with. Within a week I had lost 5 lbs, and increased my bench, squat, and deadlifts by 20%. I honestly feel like I'm half my age, which my wife was of course thrilled about. I'm sharp as a shark's tooth, and haven't been this clear mentally in years. I now look forward to my workouts, and my work.

~ Troy F. Chicago, IL

Everyone that works here is extremely nice and very knowledgeable. Already seeing a difference in my health and its only been a month. Thanks!

~ Garrett S. Chicago, IL

The most important thing to me is I've been on TRT with Chicagoland Men's Health for about 6 months, I've lost about 12lbs, my waist has shrunk from 34" to a 30" and my muscle tone hasn't been this good in 15 years.

~ TI F. Woodridge, IL

I've been on this program for 4 months and I feel amazing. My sleep, workouts, libido, and my mood have gotten a lot better. I can't imagine not being on this stuff.

~ Ray F. Chicago, IL

My energy level immediately spiked as in right after my first injections of b12 and testosterone. My sleep requirement has plummeted from needing 7-8 hours to needing 5-6 and I don't get tired during the day anymore. I am already looking and feeling stronger. My stamina has increased greatly.

~ Aaron K. Chicago, IL

It's been a little over 6 months and I've lost 25+ pounds of fat and gained easily 10 pounds of muscle. I do workout 3 x a week and also do yoga. My gut is almost gone and I'm shooting for a 6 pack for this spring.

~ Steven S. Chicago, IL

Read our Yelp Reviews

Safe - Affordable - Comprehensive - Convenient